What is this medication for?

Cholestyramine resin belongs to the class of medications known as bile acid sequestrants. When used in addition to diet and exercise, this medication helps to reduce bad cholesterol levels in the blood called low-density lipids (LDL). It works by binding to cholesterol-like substances, called bile acids, in the intestines and preventing them from being absorbed into the body.

Cholestyramine resin may be used for symptomatic control of bile-induced diarrhea due to short bowel syndrome and may also be used to relieve itchiness associated with partial blockage of bile ducts.

Your doctor may have suggested this medication for conditions other than those listed here. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it. Do not stop taking this medication without consulting your doctor.

What form(s) does this medication come in?

Questran® is available as:

• powder (oral)
• 4 g resin/packet
• 4 g resin/scoopful

Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.

How should I use this medication?

The recommended dose of cholestyramine resin is 4 g (1 packet) one to six times daily depending on circumstances. The powder must be mixed with water (120 mL to 180 mL for the regular powder and 60 mL to 90 mL for the "light" powder) or other fluids (milk, fruit juice, or other non-carbonated beverage). It may also be mixed with highly fluid soups or pulpy fruits with a high moisture content such as applesauce or crushed pineapple.

Other medicines should be taken at least one hour before or four to six hours after cholestyramine resin. Cholestyramine should never be taken in its dry form. The color of cholestyramine resin may vary somewhat from batch to batch but this does not affect the performance of the product.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Who should NOT take this medication?

Cholestyramine resin should not be taken by those who:

• are allergic to cholestyramine powder or any of its ingredients
• have bile ducts that are blocked completely